DriftDB

An open, longitudinal dataset of cortical population activity tracked over six weeks.

datasetopen datatwo-photon

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DriftDB is a curated dataset of two-photon calcium imaging from mouse visual cortex, recorded from the same neurons across six weeks during a stable discrimination task. It is the dataset behind our 2026 work on representational drift.

What’s inside

~4,000 neurons tracked across 30+ sessions per animal (6 animals).
Aligned ROIs, deconvolved activity, and full behavioral logs.
A NWB-formatted release plus loader utilities for NeuroDyn.

We release DriftDB under CC-BY so the community can test theories of drift and stability without re-collecting expensive longitudinal data.